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Papers

The Committee aims to publish papers where appropriate (except items where data was provided in confidence). These papers have been drafted by the secretariat and do not necessarily represent the veiws of the Committee or government departments. The papers are published without the appended references which are subject to copyright of the publishing journals.

Working Papers will be replaced when final versions are available

WP Draft Minutes of meeting held on 10 April 2008 pdf logo

  • CC/08/2 - Second draft working paper on chlorinated drinking water and cancer pdf logo
  • CC/08/3 - IPCS Mode of Action Human Relevance Framework pdf logo
  • CC/08/6 - Initial discussion paper on the assessment of chemical mixtures pdf logo
  • CC/08/7 - Second draft working paper pdf logo
  • CC/08/8 - 1,3-butadiene and non-Hodgkin's lymphoma: review of the evidence for IARC's reclassification of 1,3-butadiene to Group 1 carcinogen pdf logo
  • CC/08/9 - Revision of OECD test guidelines for carcinogenicity studies pdf logo
  • CC/08/10 - Mechanisms contributing to the synergism of alcohol and tobacco in human cancers pdf logo
  • CC/08/11 - Excess Mortality in Two-Year Rodent Carcinogenicity Studies pdf logo
  • CC/08/12 - Revision of 1981 OECD Test Guidelines TG 451, (Chronic Carcinogenicity Study in Rodents), TG 452 (Long-Term Chronic Toxicity Study in Rodents by Oral Administration) and TG 453 (Combined Chronic Toxicity/Carcinogenicity Studies) pdf logo
  • CC/08/13 annex A annex C - Pyrrolizidine Alkaloids in Food - Initial Assessment of Carcinogenicity pdf logo
  • CC/08/14 - Proposed strategy for reviewing carcinogen-carcinogen mixtures pdf logo
  • CC/08/15 - Update review of "Cancer incidence near municipal solid waste incinerators" pdf logo

2007

  • CC/07/1 - Assessing the risks of acute or short-term exposure to carcinogenspdf logo
  • CC/07/3 - Draft Working Paper on Prostate Cancer and Pesticide Exposure pdf logo
  • CC/07/4 - Technical guidance for derivation of DNELs and risk characterisation of non-threshold effects in the context of REACH pdf logo
  • CC/07/07 - Non-Hodgkin's review: overview paper pdf logo
  • CC/07/08 - Further consideration of the MOE approach for communicating the risks of exposure to genotoxic carcinogens pdf logo
  • CC/07/09 - Formaldehyde: an update on current assessment of carcinogenicity pdf logo
  • CC/07/10 - Revised Code of Conduct for observers pdf logo
  • CC/07/11 - Epidemiological studies of chlorinated drinking water and cancer pdf logo
  • CC/07/12 - Toxicogenomics: A selective update of the literature since 2004 pdf logo
  • CC/07/13 pdf logo - Folic acid - further papers
  • CC/07/14 pdf logo Annex 1 pdf logo Annex 2 pdf logo Annex 3 pdf logo - Further consideration of the MOE approach
  • CC/07/15 pdf logo - Draft working paper
  • CC/07/16 pdf logo - Paper by Vineis et al (2007) on "Exposure to solvents and risk of non-Hodgkin's lymphoma: Clues on putative mechanisms"
  • CC/07/17 pdf logo - Papers on QSAR predictive models for carcinogens
  • CC/07/18 pdf logo - Horizon scanning exercise 2007
  • CC/07/19 pdf logo - Draft working paper on chlorinated drinking water and cancer

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2006

  • CC/06/1 and covertable plus addition for coc pdf logo - RCEP
  • CC/06/3 - Testicular cancer - Overview paper pdf logo
  • CC/06/6 - Ramazzini study on the carcinogenicity of aspartame pdf logo
  • CC/06/8 pdf logo - Age-related differences in susceptibility to carcinogenesis
  • CC/06/9 pdf logo - Revised procedure for holding committee meetings in open session
  • CC/06/10 pdf logo - "Tissue Organisation Field Theory" of carcinogenesis
  • CC/06/12 pdf logo - "Creative Accounting": Report by People for the Ethical Treatment of Animals (PETA)
  • CC/06/13 pdf logo - Initial discussion on comparative risk assessment
  • CC/06/17 pdf logo - Ramazzini study on the carcinogenicity of aspartame - Further information
  • CC/06/18; annex 1 CC/93/29 + CC/94/7 pdf logo - Betel quid, Pan Masala and areca nut chewing
  • CC/06/19 annex 1 pdf logo - Acute T25 - Possible approach to potency ranking of single exposure genotoxic carcinogens
  • CC/06/20 pdf logo - Comparative Risk Assessment: Application of the MOE approach for communicating the risks of exposure to genotoxic carcinogens
  • CC/06/21 pdf logo - Horizon scanning exercise 2006
  • CC/06/22 annex 2 published by defra PS2609 pdf logo - Report on prostate cancer and pesticide exposure

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2005

  • CC/05/2: Carcinogenesis mode of action & human relevance framework pdf logo
  • CC/05/3: Paper by Knox on childhood cancers & atmospheric carcinogens pdf logo
  • CC/05/5: Overview of nanomaterial toxicology pdf logo + HSE review
  • CC/05/6: Single/short term exposure to carcinogens pdf logo
  • CC/05/7: Expert opinions on trends in childhood cancer incidence pdf logo
  • CC/05/8: Review of the possible associations between childhood leukaemia and residence near sources of traffic exhaust and petrol fumes pdf logo
  • CC/05/10: Cholangiocarcinoma: Pathogenesis in humans and rats pdf logo
  • CC/05/12: Human relevance framework: suggestions for additional work pdf logo
  • CC/05/13: COC response to EFSA Scientific Committee pdf logo
  • CC/05/14: Draft Statement on the review of the possible association between
    childhood leukaemia and residence near sources of traffic exhaust and petrol fumes pdf logo
  • CC/05/15: Styrene: Mode of action evaluation: Lung tumours in mice pdf logo
  • CC/05/16: The carcinogenicity of perfluoroalkyl acids - perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) pdf logo
  • CC/05/17: Horizon Scanning 2005 pdf logo
  • CC/05/18: Draft Working Paper on Nanomaterial Toxicology pdf logo
  • CC/05/19: Statement of joint meeting 9 June 2005. Use of target organ mutagenicity data in carcinogenic risk assessment pdf logo
  • CC/05/20: Review of the recent data on the quantitative relationship between alcohol consumption and squamous cell carcinoma pdf logo
  • CC/05/22: Carcinogenicity of Furan pdf logo
  • CC/05/23: PFOA pdf logo
  • CC/05/24: Opinion of the Scientific Committee on a request from EFSA related to a Harmonised Approach for Risk Assessment of Substances Which are both Genotoxic and Carcinogenic pdf logo

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2004

  • CC/04/2: Prostate Cancer: Additional data and 1st draft statement pdf logo
  • CC/04/3: Organochlorines and risk of breast cancer: Additional Information and 1st draft statement pdf logo
  • CC/04/4: 1,3-Dichloropropanol pdf logo
  • CC/04/5: Gene expression profiling in rats exposed to main stream smoke pdf logo
  • CC/04/6: Gene expression profiling in rats exposed to main stream smoke pdf logo
  • CC/04/12: Prostate Cancer: Occupational exposure to PAHs pdf logo
  • CC/04/13: Prostate Cancer: Review of rubber industry pdf logo
  • CC/04/14: Oesophageal cancer: Initial overview paper pdf logo
  • CC/04/15: Draft COC guidelines: Response to consultation pdf logo
  • CC/04/18: Malachite Green/Leucomalachite green pdf logo
  • CC/04/30: Re-assessment of toxicological testing of tobacco products pdf logo
  • CC/04/31: Childhood Cancer - Overview paper pdf logo
  • CC/04/32: Horizon scanning paper pdf logo
  • CC/04/37: Childhood leukaemia and environmental exposures pdf logo

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2003

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2001

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2000

ILSI's Collaborative research program on alternative models for carcinogenicity assessment. Presentation to COC on 24 June 1999 by Dr Denise Robinson (HESI,ILSI) (COC/99/ILSI)

Supporting papers to Alcohol and Breast Cancer statement (COC/00/S4) prepared by the DH Toxicology Unit, Imperial College of Science and Technology:

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